Table 3. Brain regions showing significantly altered functional connectivity in SCI patients.
| Seed ROI (gyrus) | SMN Connected Region | Side | Talairach coordinate (RAI) | Cluster size (mm3) | Peak t value | ||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| SCI patients < controls | |||||||
| R Precentral | Precentral gyrus | R | -47 | 16 | 43 | 15392 | -4.16 |
| Postcentral gyrus | R | -24 | 51 | 48 | -4.29 | ||
| SMA | R | -10 | 22 | 67 | -2.31 | ||
| Superior parietal lobule | R | -23 | 53 | 48 | -4.33 | ||
| Paracentral lobule | R | -10 | 36 | 68 | -2.81 | ||
| Postcentral gyrus | L | 17 | 37 | 71 | -3.55 | ||
| Paracentral lobule | L | 10 | 42 | 68 | -3.91 | ||
| L Precentral | Precentral gyrus | L | 31 | 25 | 66 | 4664 | -3.92 |
| Postcentral gyrus | L | 19 | 35 | 71 | -3.75 | ||
| Superior parietal lobule | L | 17 | 49 | 61 | -3.34 | ||
| Paracentral lobule | L | 9 | 41 | 64 | -3.38 | ||
| Precentral gyrus | R | -35 | 21 | 63 | 6928 | -3.43 | |
| Postcentral gyrus | R | -14 | 41 | 55 | -3.65 | ||
| Superior parietal lobule | R | -25 | 59 | 62 | -4.35 | ||
| Paracentral lobule | R | -11 | 41 | 57 | -3.54 | ||
| L Postcentral | Precentral gyrus | L | 25 | 21 | 51 | 9968 | -3.94 |
| Postcentral gyrus | L | 27 | 39 | 47 | -3.27 | ||
| Superior parietal lobule | L | 19 | 57 | 29 | -3.99 | ||
| Paracentral lobule | L | 8 | 38 | 64 | -2.71 | ||
| Precentral gyrus | R | -35 | 30 | 52 | 6840 | -3.35 | |
| Postcentral gyrus | R | -35 | 30 | 49 | -3.51 | ||
| Superior parietal lobule | R | -25 | 61 | 60 | -4.58 | ||
| SCI patients > controls | |||||||
| L Postcentral | Thalamus | L | 12 | 31 | 4 | 6008 | 3.50 |
| Thalamus | R | -13 | 29 | 6 | 3.90 | ||
SCI: spinal cord injury; ROI: region of interest; SMN: sensorimotor network; RAI: right-anterior-inferior; SMA: supplementary motor area; p < 0.05, corrected by 3dClustSim.