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. 2016 Mar 8;11(3):e0150418. doi: 10.1371/journal.pone.0150418

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© 2016 Li et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) An unsupervised, hierarchical cluster heat map showed 17 differently expressed miRNAs between 4 IPF lungs and 3 normal lungs. Rows represent statistically significant (P<0.05) differentially expressed miRNAs, and columns represent patients and controls. Down-regulated miRNAs are shown in progressively brighter shades of green, depending on the fold difference. Up-regulated miRNAs are shown in progressively brighter shades of red. The names of dysregulated miRNAs are provided in the right of the heat map. An arrow is to denote miR-130b-3p. (B) Quantitative real-time polymerase chain reaction (qRT-PCR) confirmation of the microarray results demonstrated significant change of miR-130b-3p in lung tissues. *P<0.05.