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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2015 Jul 10;89:1–7. doi: 10.1016/j.freeradbiomed.2015.07.004

Figure 2. Endothelial Nox4 protects from atherosclerosis.

Figure 2

Aorta were harvested from ApoE−/− and ApoE−/− + EC Nox4 mice and Oil Red O staining was performed after 12 weeks (A) or 24 weeks (B) of a Western diet. The total aortic lesions and each section of the aorta were quantified for % lesion area (mean ± SE; n = 7–12 / group *p < 0.05). Aortic root sections were harvested at 5,12, and 24 weeks on a Western diet and stained with Masson’s trichrome (C) and MOMA-2 (D) (mean ± SE; n = 3–5 / group; 3–5 sections/mouse).