Table 3b.

Association Between CKDcys and Blood Pressure Measurements, by antihypertensive medication use

Ambulatory Blood Pressure Monitoring
	Systolic dipping (%)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	−5	−9 to −1	0.02	−3	−8 to 1	0.2	−2	−8 to 2	0.2
CKDcys present, med use +	−2	−5 to 0	0.08	−2	−5 to 1	0.1	−1	−4 to 2	0.4

	Mean 24-hour DBP (mmHg)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	−4	−8 to 1	0.09	−1	−5 to 3	0.7	−2	−7 to 2	0.3
CKDcys present, med use +	−5	−8 to −3	<0.001	−3	−5 to 0	0.05	−2	−5 to 1	0.2

	Mean 24-hour SBP (mmHg)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	5	−2 to 13	0.2	4	−4 to 12	0.37	0	−8 to 7	0.9
CKDcys present, med use +	1	−3 to 5	0.5	1	−3 to 6	0.66	0.35	−4 to 5	0.9

	Mean 24-hour pulse pressure (mmHg)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	9	3 to 15	0.004	5	−2 to 11	0.1	2	−4 to 8	0.6
CKDcys present, med use +	7	3 to 10	<0.001	4	0 to 8	0.06	2	−2 to 6	0.2

In-Clinic Measurements
	Mean clinic DBP (mm Hg)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	−3	−9 to 2	0.2	−2	−9 to 4	0.5	−5	−11 to 1	0.1
CKDcys present, med use +	−5	−8 to −2	0.002	−1	−5 to 2	0.36	−1	−5 to 2	0.4

	Mean clinic SBP (mm Hg)
	Unadjusted			Age-Adjusted			Model 1*
	β	95% CI	p-value	β	95% CI	p-value	β	95% CI	p-value
CKDcys present, med use −	7	−3 to 17	0.2	1	−9 to 12	0.8	−3	−13 to 7	0.6
CKDcys present, med use +	4	−1 to 9	0.1	3	−2 to 9	0.3	2	−4 to 7	0.6

^*Adjusted for age, sex, race, BMI and the presence of: diabetes, cardiovascular disease and smoking history