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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Front Neuroendocrinol. 2015 Oct 9;40:42–51. doi: 10.1016/j.yfrne.2015.10.001

Figure 9. Effect of aging on aromatase availability in the human brain.

Figure 9

Top: Specific tracer uptake in thalamus (large arrow) and cortical white matter (arrowhead) in a 67 years old male subject. Left=baseline study, right = blocking study. These punctate accumulations of tracer only appear in older subjects. Axial slices, level of thalamus. Bottom: Panel on left displays the relationship between age and total distribution volume (VT) in occipital cortex, fitted to a straight line with R=0.61 and p<0.015. The relationship of VT with age in cortical white matter (right panel) is best fit by a polynomial 2nd order equation, with R=0.59 and p<0.05. Occ=occipital cortex, wm=cortical white matter.