Table 2.
Top differentially expressed genes
| a. Top significantly upregulated genes in samples with HS
| ||||
|---|---|---|---|---|
| Log Fold Change | Log Counts Per Million | P-Value | Adjusted | |
| CDKN1C | 3.53 | 4.35 | 1.69E-08 | 2.13E-04 |
| RP11-466P24.7 | 3.19 | 5.87 | 1.09E-07 | 4.98E-04 |
| SV2C | 4.16 | 4.66 | 1.18E-07 | 4.98E-04 |
| PCSK1 | 4.31 | 6.92 | 1.69E-07 | 5.24E-04 |
| SCRN1 | 1.93 | 6.19 | 2.08E-07 | 5.24E-04 |
| KIAA1217 | 1.85 | 5.21 | 2.80E-07 | 5.26E-04 |
| ELAVL2 | 4.00 | 4.90 | 2.92E-07 | 5.26E-04 |
| GNG4 | 2.90 | 4.97 | 3.83E-07 | 6.04E-04 |
| QPCT | 2.31 | 5.68 | 6.34E-07 | 8.88E-04 |
| KIT | 2.49 | 4.68 | 7.38E-07 | 9.31E-04 |
| STRIP2 | 1.85 | 4.93 | 1.51E-06 | 1.73E-03 |
| ARHGAP36 | 3.34 | 8.10 | 8.06E-06 | 6.77E-03 |
| CCBE1 | 2.92 | 1.80 | 1.00E-05 | 7.91E-03 |
| MIR22HG | 1.99 | 4.57 | 1.14E-05 | 8.46E-03 |
| SPRY1 | 3.05 | 2.21 | 1.29E-05 | 9.04E-03 |
| b. Significantly downregulated genes in samples with HS
| ||||
|---|---|---|---|---|
| Log Fold Change | Log Counts Per Million | P-Value | Adjusted | |
| ANKRD20A19P | −1.75 | 5.15 | 5.70E-06 | 5.57E-03 |
| FST | −3.53 | 2.91 | 5.74E-06 | 5.57E-03 |
| ANO3 | −1.68 | 8.04 | 6.24E-06 | 5.62E-03 |
| GRM2 | −1.68 | 4.66 | 5.62E-05 | 2.44E-02 |
| ATP2B4 | −1.39 | 8.32 | 6.82E-05 | 2.48E-02 |
| RP11-369E15.3 | −2.08 | 3.12 | 9.29E-05 | 2.72E-02 |
| SLC3A1 | −1.77 | 1.83 | 9.82E-05 | 2.81E-02 |
| JAG1 | −1.23 | 6.54 | 1.28E-04 | 3.36E-02 |
| GNAL | −1.60 | 6.44 | 1.91E-04 | 4.43E-02 |
| PCP4 | −1.51 | 7.83 | 2.30E-04 | 4.69E-02 |
| SLC5A12 | −2.53 | 2.16 | 2.62E-04 | 5.00E-02 |