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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Mol Cancer Ther. 2016 Jan 28;15(3):392–401. doi: 10.1158/1535-7163.MCT-15-0667

Figure 2. Effects of CAR activation on the expression of genes responsible for CHOP disposition in HPH and lymphoma cell lines.

Figure 2

The expression of CYP2B6, CYP3A4, CYP3A5, CBR1, CBR3, MDR1, and CAR mRNA was measured in human primary hepatocytes as well as three representative lymphoma cell lines (SU-DHL-4, SU-DHL-6, and OCI-L-Y-3) following treatment with vehicle control (0.1% DMSO) or CITCO (1 μM) as described in the Materials and Methods. Expression of these genes was analyzed with RT-PCR. Data represent the mean ± S.D. of three independent experiments (***, p < 0.001).