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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Cardiovasc Pharmacol. 2016 Mar;67(3):260–265. doi: 10.1097/FJC.0000000000000343

Figure 4.

Figure 4

Initiation of VT is faster in HF than naïve rabbits with saline pretreatment. Representative ECG traces at the time of VT initiation. Paired ECGs for HF (top) and naïve (bottom) rabbits are shown during pretreatment with saline (Vehicle, left) and KN-93 (right). Shown in each trace are the last 3 sinus beats preceding VT initiation. Note that during treatment with vehicle, the VT initiation (mean of first 5 CLs of VT) is faster in HF than naïve; this difference was diminished during pretreatment with KN-93. Mean cycle lengths of VT initiation shown for HF vehicle and KN93, and naïve vehicle and KN93 were 193, 254, 402 and 304 ms, respectively.