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. Author manuscript; available in PMC: 2017 Mar 7.
Published in final edited form as: Mol Pharm. 2016 Jan 22;13(3):809–818. doi: 10.1021/acs.molpharmaceut.5b00723

Figure 5.

Figure 5

Daily dosing of mice with M1 (681 mg/kg) or ABZ (up to 3.2 mg/kg) for 14 days did not result in significant weight loss. Seven female Swiss Webster mice per group were injected by weight, once daily through IP route with 681 mg/kg of M1 (closed circle) or 0.5 mg/kg (closed upward triangle), 1.4 mg/kg (closed downward triangle), 2.3 mg/kg (closed diamond) and 3.2 mg/kg (open upward triangle) of ABZ formulated with M1. An untreated group (closed squares) was also included. Twenty percent weight loss (solid line) indicates humane endpoint. The average and standard deviation of mouse weight per experimental group (n=7) is plotted.