Figure 3.

Alternatively spliced genes with age were enriched for post‐transcriptional modifications including the spliceosome pathway. (A) The mouse KEGG spliceosome pathway with affected components highlighted in pink and AS genes for each component. (B) IPA network analysis of AS genes and main associated network functions. Highlighted underlined in red are the AS genes and components involved in RNA post‐transcriptional processes such as splicing. (C) RNA post‐transcriptional modification functions and the corresponding network components and genes that were identified as being alternatively spliced in aging.