Figure 1.

Cochlear expression of Trail and Dr5. (A) mRNA expression with age, relative to Trail mRNA expression at P5. w = weeks. n = 5 mice. replicates per age. *P < 0.05. Data are plotted as mean ± SD. (B) TRAIL and DR5 protein expression at 5 days (n = 4 mice) and 7 weeks (n = 3 mice) of age. (C) In situ hybridization for Trail (a, b, c), Dr5 (e, f, g), and antisense controls for Trail (d) and Dr5 (h) in cochlear cross sections. Images of the organ of Corti (b, f) and SGNs (c, g). Scale bar: 100 μm (C(a), (d), (e), (h)) or 20 μm (C(b‐c), (f‐g)). The experiment was repeated in cochlear samples from 3 mice.