Table 2.
Drugs identified as matching or opposing the transcriptional profile of CR based on data from each dose and cell line
CMap name and cell line | Mean | P‐value |
---|---|---|
Sirolimus – MCF7 | −0.491 | 0 |
Tanespimycin – MCF7 | 0.378 | 0 |
Trichostatin A – PC3 | −0.276 | 0 |
Geldanamycin – MCF7 | 0.445 | 0.00002 |
Mean shows the level of match and the direction of the match based on the average of all arrays at each dosage, with each cell line, for each drug within the CMap; positive values indicate a match, whereas negative ones indicate an opposite profile. Probability values indicate the statistical significance of the match. Only statistically significant drugs after Benjamini correction are shown. Full results are in Table S2.