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. 2016 Jan 10;15(2):291–300. doi: 10.1111/acel.12435

Figure 2.

Figure 2

Phenotypic characterization of Tim‐3‐expressing CD8+ T cells in aged mice. (A, B) The expression of CD44 and CD62L in CD8+ T cells from aged and young mice (left), and in each aged CD8+ T‐cell subset (right) (n = 5). Representative CD3+ CD8+‐gated FACS plots are shown with percentages of each quadrant; CD44lo CD62Lhi (Naïve), CD44hi CD62Lhi (Central memory), CD44hi CD62Llo (Effector memory), and CD44lo CD62Llo (Revertant) (A). The statistical graph shown in (B). (C) The expression of various surface molecules on each aged CD8+ T‐cell subset was analyzed by flow cytometry. One‐way ANOVA with Bonferroni's post hoc (B, C). Error bars represent SEM. *< 0.05; **< 0.01; ***< 0.001. All data are representative of three independent experiments