Table 1.
Pathway annotations associated with experimentally validated targets of miRNAs upregulated in aged hippocampus
| Gene ontology | Gene Count | P‐value |
|---|---|---|
| Pathways in cancer | 11 | 4.30E‐07 |
| TGF‐beta signalling pathway | 7 | 1.40E‐06 |
| MAPK signalling pathway | 7 | 7.70E‐04 |
| Wnt signalling pathway | 5 | 3.60E‐03 |
| Chronic myeloid leukema | 4 | 4.20E‐03 |
| Colorectal cancer | 4 | 5.90E‐03 |
| Cell cycle | 4 | 1.70E‐02 |
| Neurotrophin signalling pathway | 4 | 1.80E‐02 |
| Endometrial cancer | 3 | 2.10E‐02 |
| Acute myeloid leukaemia | 3 | 2.50E‐02 |
| Pancreatic cancer | 3 | 3.90E‐02 |
| Adherens junction | 3 | 4.30E‐02 |
| ErbB signalling pathway | 3 | 5.40E‐02 |
| Prostate cancer | 3 | 5.80E‐02 |
| GnRH signalling pathway | 3 | 6.60E‐02 |
| Toll‐like receptor signalling pathway | 3 | 6.80E‐02 |
| T‐cell receptor signalling pathway | 3 | 9.30E‐02 |