Table 2.
Estimates of unilateral hippocampal cell numbers and sampling parameters.
| DBA | C57BL/6 | House mouse | Highveld mole-rat | Cape mole-rat | Naked mole-rat | Sand rat | Hamster | Cotton rat | Muskrat | Yellow-necked wood mouse | Bank vole | Marmoset | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Granule cells | 409,981 | 438,187 | 476,984 | 588,647 | 48,8676 | 380,255 | 611,424 | 497,717 | 613,446 | 1415,956 | 1437,135 | 204,2739 | 249,8487 |
| SD | 22,614 | 137,143 | 72,686 | 93,514 | 77,599 | 34,806 | 112,574 | 88,880 | 75,937 | 82,545 | 213,879 | 211,439 | 431,224 |
| Mean CE | 0.13 | 0.13 | 0.09 | 0.08 | 0.11 | 0.07 | 0.10 | 0.09 | 0.08 | 0.10 | 0.07 | 0.07 | 0.07 |
| CE2/CV2 | 5.45 | 1.06 | 0.34 | 0.32 | 0.45 | 0.70 | 0.30 | 0.27 | 0.42 | 2.76 | 0.24 | 0.40 | 0.18 |
| Frame/grid size | 7/100 | 7/100 | 10/100 | 12/140 | 18/324 | 10/120 | 12/160 | 12/120 | 12/120 | 45/180 | 10/210 | 10/210 | 15/120 |
| Sections | 12 (0.8) | 11(1.6) | 20 (1.1) | 15 (0.2) | 16 (0) | 21 (0.4) | 16 (1.2) | 15 (0.8) | 16 (0.6) | 16 (2.8) | 31 (1.8) | 25 (4.7) | 13 (1.5) |
| Cells counted | 145 (60) | 144 (16) | 204 (99) | 216 (30) | 164 (62) | 353 (23) | 210 (40) | 221 (27) | 240 (34) | 213 (52) | 263 (33) | 380 (88) | 697 (78) |
| Hilar cells | 10,487 | 13,029 | 18,561 | 53,219 | 71,216 | 19,365 | 37,742 | 26,769 | 27,658 | 104,394 | 78,578 | 53,695 | 187,457 |
| SD | 1212 | 2267 | 3099 | 5697 | 12,930 | 2765 | 5494 | 5894 | 3033 | 15,103 | 7406 | 6856 | 12,391 |
| Mean CE | 0.13 | 0.13 | 0.11 | 0.13 | 0.13 | 0.15 | 0.08 | 0.10 | 0.08 | 0.16 | 0.09 | 0.13 | 0.104 |
| CE2/CV2 | 1.37 | 0.49 | 0.47 | 1.26 | 0.60 | 1.17 | 0.33 | 0.20 | 0.58 | 1.32 | 0.82 | 1.01 | 2.52 |
| Frame/grid size | 30/70 | 30/70 | 30/70 | 40/120 | 30/150 | 40/70 | 45/140 | 45/120 | 45/120 | 45/210 | 40/170 | 40/140 | 40/200 |
| Sections | 12 (1.2) | 11 (1.6) | 9 (0.9) | 9 (0.4) | 10.6 (1.2) | 9 (0.4) | 16 (1.0) | 15 (1.7) | 15 (0.8) | 16 (2.3) | 14 (1.7) | 8 (1.0) | 13 (1.3) |
| Cells counted | 148 (48) | 126 (19) | 215 (36) | 199 (19) | 91 (21) | 386 (61) | 223 (22) | 163 (32) | 163 (11) | 171 (36) | 220 (38) | 168 (15) | 159 (19) |
| CA3 pyramids | 155,129 | 113,603 | 21,3077 | 374,376 | 55,0413 | 24,9021 | 285,537 | 171,799 | 184,583 | 432,250 | 454,510 | 409,606 | 392,291 |
| SD | 16,621 | 29,322 | 36,953 | 28,207 | 71,336 | 44,854 | 56,815 | 27,378 | 21,957 | 61,979 | 47,889 | 77,249 | 35,139 |
| Mean CE | 0.12 | 0.11 | 0.12 | 0.1 | 0.1 | 0.08 | 0.10 | 0.10 | 0.08 | 0.11 | 0.09 | 0.09 | 0.09 |
| CE2/CV2 | 1.23 | 3.71 | 0.51 | 1.61 | 0.66 | 0.18 | 0.27 | 0.36 | 0.47 | 0.61 | 0.65 | 0.26 | 0.95 |
| Frame/grid size | 11/100 | 11/100 | 11/100 | 18/160 | 15/200 | 15/130 | 25/250 | 25/160 | 25/160 | 25/260 | 15/190 | 15/140 | 30/200 |
| Sections | 15 (1.2) | 13 (1.7) | 10 (0.8) | 11 (0.4) | 12.5 (1.2) | 12 (0.4) | 18 (1.5) | 18 (1.0) | 18 (0.8) | 20 (2.9) | 14 (1.5) | 9 (0.5) | 13 (1.1) |
| Cells counted | 146 (47) | 97 (10) | 165 (20) | 153 (8) | 101 (17) | 205 (17) | 184 (39) | 179 (25) | 187 (15) | 138 (38) | 142 (14) | 185 (20) | 185 (29) |
| CA1 pyramids | 162,744 | 155,745 | 233,670 | 338,455 | 415,012 | 158,693 | 359,291 | 221,382 | 275,219 | 663,434 | 740,667 | 455,249 | 656,509 |
| SD | 21,729 | 51,368 | 56,389 | 29,375 | 132,131 | 18,884 | 70,170 | 34,246 | 11,044 | 81,379 | 91,568 | 93,897 | 41,394 |
| Mean CE | 0.13 | 0.14 | 0.10 | 0.12 | 0.12 | 0.10 | 0.11 | 0.10 | 0.08 | 0.10 | 0.10 | 0.10 | 0.12 |
| CE2/CV2 | 1.09 | 1.51 | 0.17 | 2.12 | 0.15 | 0.76 | 0.32 | 0.44 | 3.51 | 0.65 | 0.60 | 0.24 | 4.54 |
| Frame/grid size | 11/100 | 11/100 | 11/100 | 18/160 | 15/180 | 15/110 | 25/250 | 25/160 | 25/160 | 25/260 | 10/160 | 15/130 | 30/320 |
| Sections | 16 (2.8) | 13 (1.7) | 12 (0.6) | 12 (0.8) | 14 (1.4) | 13 (0.7) | 19 (1.2) | 18 (1) | 18 (0.8) | 20 (2.9) | 16 (1.6) | 10(0.5) | 14 (1) |
| Cells counted | 153 (66) | 130 (8) | 174 (23) | 141 (12) | 97 (25) | 183 (11) | 236 (7) | 230 (29) | 280 (18) | 216 (63) | 154 (14) | 230 (37) | 173 (54) |
| Subicular cells | 119,944 | 108,479 | 14,7146 | 263,138 | 30,911 | 13,1505 | 173,602 | 134,379 | 117,120 | 302,230 | 295,464 | 241,765 | 216,992 |
| SD | 12,015 | 22,932 | 32,839 | 33,554 | 62,378 | 33,019 | 28,260 | 18,230 | 9493 | 31,484 | 38,801 | 42,119 | 31,991 |
| Mean CE | 0.11 | 0.10 | 0.1 | 0.09 | 0.10 | 0.11 | 0.08 | 0.07 | 0.08 | 0.09 | 0.09 | 0.10 | 0.12 |
| CE2/CV2 | 1.16 | 0.57 | 0.21 | 0.50 | 0.26 | 0.13 | 0.25 | 0.28 | 0.95 | 0.72 | 0.42 | 0.30 | 0.67 |
| Frame/grid size | 25/140 | 18/140 | 18/140 | 20/150 | 20/190 | 20/130 | 45/320 | 45/200 | 45/190 | 45/350 | 20/180 | 20/140 | 18/240 |
| Sections | 15 (1.4) | 12 (1.7) | 12 (0.9) | 12 (0.5) | 13 (1.6) | 12 (1.1) | 18 (1.2) | 18 (0.8) | 18 (0.8) | 18 (3.4) | 15 (1.5) | 11 (0.6) | 14 (1.7) |
| Cells counted | 156 (59) | 128 (13) | 145 (24) | 154 (20) | 112 (22) | 192 (35) | 259 (100) | 286 (32) | 282 (20) | 179 (23) | 176 (23) | 183 (20) | 132 (60) |
Principle cell numbers of animals analyzed for this study. Numbers presented here are means. Frame and grid sizes are in μm. Sections and cells counted are presented as mean (SD).