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. 2016 Mar 7;23(3):228–235. doi: 10.1128/CVI.00604-15

TABLE 2.

Proportion of treatment effect on A/H3N2 influenza illness occurrence explained by assays

Case definitiona (n) Proportion of treatment effect explained by assay
HAI, vaccine virus (n = 5,752) HAI, circulating virus (n = 673) NT, vaccine virus (n = 675) NT, circulating virus (n = 675) N2 ELLA (n = 675)
Laboratory-confirmed influenza associated with RI (n = 152/123) 0.82 0.97 0.85 1.32 0.58
Laboratory-confirmed influenza associated with PD-ILI (n = 121/98) 0.95 1.13 1.12 1.81 0.75
Laboratory-confirmed influenza associated with CDC-ILI (n = 52/48) 0.86 0.65 0.75 0.99 0.51
Antigenically similar influenza associated with RI (n = 37/34) 0.48 0.47 0.32 0.49 0.53
Antigenically similar influenza associated with PD-ILI (n = 30/28) 0.50 0.65 0.41 0.75 0.65
Antigenically similar influenza associated with CDC-ILI (n = 18/17) 0.27 0.27 0.17 0.32 0.28
a

n indicates the number of cases. The first number is for the HAI vaccine virus assay, the second is for the other assays.