Table 1.
Parameter | Controls (n = 14)a | T1DM (n = 8)b | T2DM (n = 3) |
---|---|---|---|
Age (years) | 27.5 ± 1.4 | 29.4 ± 4.3 | 55.0 ± 3.5* |
Gender (male/female) | 9:5 | 4:4 | 2:1 |
Weight (kg) | 70.5 ± 2.7 | 75.2 ± 4.0 | 95.8 ± 10.9* |
Body mass index (kg/m2) | 23.5 ± 0.5 | 25.3 ± 0.9 | 31.4 ± 0.3* |
Hemoglobin A1c (%) | 5.0 ± 0.1 | 7.1 ± 0.2** | 7.0 ± 0.1* |
Insulin dose/day (units/kg/day) | N/A | 0.57 ± 0.05 | 1.24c |
Duration of diabetes (years) | N/A | 18.5 ± 2.8 | 11.7 ± 2.4 |
Estimated glomerular filtration rate—Modification of Diet in Renal Disease Study formula (ml/min/1.73 m2) | 100.7 ± 5.4 | 100.0 ± 4.1 | 90.0 ± 8.9 |
N/A not applicable
aControls: n = 9 for cross-sectional study and n = 5 for test-retest study
bT1DM patients: n = 6 for cross-sectional study and n = 2 for test-retest study
c1 of 3 with T2DM requiring insulin
*p < 0.01, control vs. T2DM
**p < 0.01, control vs. T1DM