Table 3.

Concentration–response analysis reveals that chronic menthol alters α6β2* nAChR stoichiometry

	Treatment condition
	α6-GFP, β2, β3 no drug	α6-GFPβ2DM no drug	α6-GFP, β2, β3 + menthol
EC50 value (higher sensitivity)	0.20 ± 0.07 μm	—	0.17 ± 0.04 μm
nh (higher)	1.01	—	0.78
EC50 value (lower sensitivity)	—	35.9 ± 20.7 μma	65.0 ± 4.7 μma
nh (lower)	—	0.79	2.3
Higher fraction	—	—	0.43

Values are represented as mean ± SEM.

^aEC₅₀ values are statistically different from α6-GFPβ2β3 nAChRs (no drug). p < 0.005, unpaired t test.