Figure 8.
Axonal targeting and Nrp1 expression in the OB. A, C, F, H, GFP-expressing M71 or mOR-EG glomeruli in OMP WTs (A, F) and KOs (C, H). B, D, G, I, Nrp1 staining in the OB revealed mosaic patterns in both OMP WTs and KOs and for both receptor types (B, D: M71; G, I: mOR-EG). For comparison ∼100 glomeruli for each mouse (n = 5 and n = 7 mice for M71 OMP WTs and KOs respectively and for mOR-EG OMP WTs and KOs; n = 2 mice for each genotype). E–J, Glomeruli were ranked and Nrp1 levels of GFP-positive glomeruli fell into the ∼70th percentile in all genotypes tested. p > 0.05, Wilcoxon rank sum test. All data are expressed as mean ± SEM.