Table 1.
Summary of demographic characteristics of 119 669 participants of white British ancestry with valid genetic data and height and body mass index measures available, stratified by sex. Values are numbers (percentages) unless stated otherwise
| Characteristic | All (n=119 669) | Men (n=56 652) | Women (n=63 017) | P value* |
|---|---|---|---|---|
| Mean (SD) age at recruitment, years | 56.9 (7.9) | 57.3 (8.0) | 56.6 (7.8) | <1×10−15 |
| Male sex | 56 652 (47.3) | 56 652 (100) | 63 017 (100) | – |
| Mean (SD) body mass index, kg/m2 | 27.5 (4.8) | 27.9 (4.3) | 27.2 (5.2) | <1×10−15 |
| Mean (SD) height, cm | 168.8 (9.2) | 175.7 (6.7) | 162.6 (6.2) | <1×10−15 |
| Smoking status: | ||||
| Never | 63 806 (53.3) | 27 834 (49.1) | 35 972 (57.1) | <1×10−15 |
| Former | 40 890 (34.2) | 21 162 (37.4) | 19 728 (31.3) | |
| Current | 13 332 (11.1) | 6767 (11.9) | 6565 (10.4) | |
| Missing | 1641 (1.4) | 889 (1.6) | 752 (1.2) | |
| Mean (SD) age completed full time education, years | 16.6 (2.2) | 16.6 (2.4) | 16.5 (2.0) | 2×10−9 |
| Degree level education | 53 652 (44.8) | 25 956 (45.8) | 27 696 (44.0) | 6×10−15 |
| Job class: | ||||
| Elementary occupations | 3932 (3.3) | 2054 (3.6) | 1878 (3.0) | <1×10−15 |
| Process plant and machine operatives | 3740 (3.1) | 3299 (5.8) | 441 (0.7) | |
| Sales and customer service occupations | 2658 (2.2) | 588 (1.0) | 2070 (3.3) | |
| Leisure and other personal service occupations | 963 (0.8) | 379 (0.7) | 584 (0.9) | |
| Personal service occupations | 3567 (3.0) | 404 (0.7) | 3163 (5.0) | |
| Skilled trades | 6077 (5.1) | 5404 (9.5) | 673 (1.1) | |
| Administrative and secretarial roles | 11 878 (9.9) | 2329 (4.1) | 9549 (15.2) | |
| Business and public sector associate professionals | 4631 (3.9) | 2548 (4.5) | 2083 (3.3) | |
| Associate professionals | 8388 (7.0) | 3148 (5.6) | 5240 (8.3) | |
| Professional occupations | 17 044 (14.2) | 8934 (15.8) | 8110 (12.9) | |
| Senior officials | 13 526 (11.3) | 8521 (15.0) | 5005 (7.9) | |
| Income: | ||||
| <£18 000 | 23 817 (19.9) | 10 499 (18.5) | 13 318 (21.1) | <1×10−15 |
| £18 000 to £30 999 | 26 808 (22.4) | 12 788 (22.6) | 14 020 (22.3) | |
| £31 000 to £51 999 | 27 245 (22.8) | 13 848 (24.4) | 13 397 (21.3) | |
| £52 000 to £100 000 | 20 397 (17.0) | 10 950 (19.3) | 9447 (15.0) | |
| >£100 000 | 5060 (4.2) | 2777 (4.9) | 2283 (3.6) | |
| Mean (SD) Townsend deprivation index | −1.5 (3.0) | −1.51 (3.0) | −1.45 (2.9) | <1×10−15 |
| Overall per allele height SNP association with height | 0.021 (0.021 to 0.022); P<1×10−15 | 0.022 (0.022 to 0.023); P<1×10−15 | 0.020 (0.020 to 0.021); P<1×10−15 | – |
| Overall per allele BMI SNP association with BMI | 0.022 (0.021 to 0.023); P<1×10−15 | 0.022 (0.021 to 0.024); P<1×10−15 | 0.025 (0.023 to 0.026); P<1×10−15 | – |
BMI=body mass index; SNP=single nucleotide polymorphism.
Not all five socioeconomic status measures were available in all 119 669 individuals (see supplementary table A for further information).
*For comparison between men and women; models were adjusted for age at recruitment.