Table 1.

Logistic regression analysis of the SNPs in the BDNF gene between controls and suicide completers, adjusted by age, gender and alcohol dependence syndrome status.

SNP	Model		OR	95% CI	pa
rs7124442	Geno_2dfb	TTvs. CT vs. CC	N/A	N/A	0.313
ADDc	2 CC+CT vs.TT	1.234	0.939–1.623	0.131
Dominantd	TTvs. CT+CC	1.106	0.821–1.489	0.508
Recessivee	TT+CT vs. CC	1.513	0.887–2.579	1.128
rs10767664	Geno_2df	AAvs. TA vs. TT	N/A	N/A	0.161
ADD	2 TT+TA vs.AA	1.296	0.954–1.761	0.097
Dominant	AAvs. TA+TT	1.287	0.955–1.736	0.098
Recessive	AA+TA vs. TT	1.559	0.854–2.847	0.148
rs962369	Geno_2df	TTvs. CT vs. CC	N/A	N/A	0.813
ADD	2 CC+CT vs.TT	1.039	0.762–1.415	0.811
Dominant	TTvs. CT+CC	0.940	0.698–1.267	0.686
Recessive	TT+CT vs. CC	1.113	0.606–2.045	0.730
rs12273363	Geno_2df	TTvs. CT vs. CC	N/A	N/A	0.905
ADD	2 CC+CT vs.TT	1.085	0.682–1.728	0.730
Dominant	TTvs. CT+CC	0.977	0.706–1.352	0.889
Recessive	TT+CT vs. CC	1.191	0.472–3.008	0.711
rs908867	Geno_2df	CCvs. TC vs. TT	N/A	N/A	0.838
ADD	2 TT+TC vs.CC	0.956	0.464–1.970	0.902
Dominant	CCvs. TC+TT	0.886	0.592–1.324	0.554
Recessive	CC+TC vs. TT	0.930	0.219–3.949	0.922
rs1491851	Geno_2df	CCvs. TC vs. TT	N/A	N/A	0.623
ADD	2 TT+TC vs.CC	0.994	0.813–1.216	0.953
Dominant	CCvs. TC+TT	1.094	0.795–1.504	0.581
Recessive	CC+TC vs. TT	0.908	0.642–1.284	0.583

OR: odds ratio; CI: confidence interval.

^ap-values are not corrected for multiple testing (Bonferroni); bold: major allele homozygotes.

^bGeno_2df (general genotypic model): major allele homozygotes vs. heterozygotes vs. minor allele homozygotes.

^cADD (additive model, where each copy of the minor allele alters the risk in an additive form; a combination of the minor allele homozygotes with weight 2+heterozygotes is compared to major allele homozygotes): 2× minor allele homozygotes+heterozygotes vs. major allele homozygotes.

^dDominant: major allele homozygotes vs. heterozygotes+minor allele homozygotes.

^eRecessive: major allele homozygotes+heterozygotes vs. minor allele homozygotes.