Table 1.
Antimutagenicity of white shrimp muscle-crude chloroform extract and its methanolic and hexanic fractions tested on Salmonella typhimurium tester strains.
| Dose (mg/plate) | Crude extract | Methanolic fraction | Hexanic fraction |
|---|---|---|---|
| TA98 | |||
| 5 | 94.6 ± 1.1a | 95.6 ± 0.6a | 67.8 ± 1.1b |
| 0.5 | 12.6 ± 12.6 | 31.3 ± 13.8 | 54.7 ± 14.3 |
| 0.05 | 10.2 ± 12.4 | 10.2 ± 4.2 | −10.2 ± 9.8 |
|
| |||
| TA100 | |||
| 5 | 95.3 ± 2.4a | 95.9 ± 1.9a | 32.7 ± 8.0a |
| 0.5 | 2.5 ± 14.6 | 11.5 ± 6.0 | 0.2 ± 11.1 |
| 0.05 | −14.5 ± 17.2 | −8.6 ± 12.8 | −34.9 ± 9.1 |
Results are presented as the percentage of inhibition of AFB1 mutation and are representative of three repetitions.
Values with different letters within a row are significantly different (P < 0.05). Spontaneous revertants were 31 ± 3 and 117 ± 6, and AFB1 control (500 ng) induced 625 ± 26 and 958 ± 27 revertants/plate for TA98 and TA100, respectively.