Table 3.

Baseline characteristics of the patients included in the comparison and model-development analysis.

	The comparison and model development set		p value	Other formulas
	TSS group	KBG group
Number of patients	60	68	N/A	86
Age at consultation
Mean ± SD	33.3 ± 7.9	32.5 ± 8.7	0.595∗	33.0 ± 8.1
Median	33	33	0.742†	33
Range	17–50	12–50		13–49
N/A	0 (0.0)	0 (0.0)		0 (0.0)
Age at menarche, years
Mean ± SD	12.2 ± 1.5	12.3 ± 1.6	0.753∗	12.7 ± 1.6
Median	12	12	0.932†	12
Range	9–16	9–17		9–17
N/A	0 (0.0)	2 (2.9)		2 (2.3)
Menstrual cycle, days
Mean ± SD	29.0 ± 5.7	29.3 ± 3.6	0.772∗	28.9 ± 4.5
Median	28	28	0.771†	28
Range	16–60	25–45		17–60
N/A	6 (10.0)	16 (23.5)		10 (11.6)
Bleeding period, days
Mean ± SD	5.8 ± 1.3	5.9 ± 1.9	0.841∗	5.5 ± 1.6
Median	6	6	0.747†	5
Range	3–9	3–14		3–14
N/A	4 (6.7)	9 (13.2)		7 (8.1)
BMI, kg/m2
Mean ± SD	19.8 ± 2.3	21.6 ± 3.5	0.001∗	20.6 ± 2.9
Median	19.4	21.0	0.000†	20.0
Range	15.9–26.7	17.0–39.8		15.6–30.1
<18.5 (slim)	21 (35.0)	6 (8.8)	0.000‡	26 (30.2)
≥25 (obese)	2 (3.3)	9 (13.2)	0.060‡	7 (8.1)
N/A	2 (3.3)	1 (1.5)		4 (4.7)
Use of OCs
No	54 (90.0)	63 (92.6)	0.754‡	77 (89.5)
Yes	6 (10.0)	5 (7.4)		9 (10.5)
Delivery
No	54 (90.0)	62 (91.2)	1‡	75 (87.2)
Yes	6 (10.0)	6 (8.8)		11 (12.8)
Abortion
No	53 (88.3)	61 (89.7)	1‡	74 (86.0)
Yes	7 (11.7)	7 (10.3)		12 (14.0)
Diagnosed organic disease
No	52 (86.7)	53 (77.9)	0.251‡	81 (94.2)
Endometriosis	6 (10.0)	8 (11.8)	0.785‡	4 (4.7)
Adenomyosis	2 (3.3)	8 (11.8)	0.103‡	2 (2.3)
Infertility (primary and secondary)
No	59 (98.3)	64 (94.1)	0.370‡	81 (94.2)
Yes	1 (1.7)	4 (5.9)		5 (5.8)

TSS, tokishakuyakusan; KBG, keishibukuryogan; N/A, not available; BMI, body mass index; OCs, oral contraceptives.

Findings are expressed as mean ± SD, median, range, or number with percentage in parentheses.

p values were calculated using ^∗ t-test, ^†Wilcoxon's rank sum test, and ^‡Fisher's exact test.