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. 2015 Nov 10;65(1):53–62. doi: 10.1538/expanim.15-0062

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©2016 Japanese Association for Laboratory Animal Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

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Fig. 2. — Cancer induction in the BALB/c-congenic ANP32B-deficient mouse. (A) Kaplan-Meier survival curve of DMBA-treated BALB/c-congenic wild-type (+/+) and Anp32b-null (−/−) mice. Survival was determined by absence of defined humane endpoints. No genotype effect was evident at statistically significant levels. (B) Incidence of different tumor types in DMBA-treated mice. Mam, mammary; Ov, ovarian; Lym, lymphoid; Pul, pulmonary; CSCC, cutaneous squamous cell carcinoma. *, P<0.05 by Chi-square test.