Table 1. Strain-dependent survival of Anp32b-deficient mice. Mendelian ratios of Anp32b heterozygote intercrosses from six-generation (A) FVB/N and (B) BALB/c congenic backgrounds.
(A) FVB/N Congenic | (B) BALB/c Congenic | ||||||
---|---|---|---|---|---|---|---|
Anp32b genotype | Anp32b genotype | ||||||
+/+ | +/– | –/– | +/+ | +/– | –/– | ||
Expected | 62 | 123 | 62 | 83 | 167 | 83 | |
Observed | 92 | 148 | 6 | 102 | 181 | 50 |
(A) Chi-square test: P < 10-15, (B) Chi-square test: P < 10-4.