Table 2. Changes in clinical chemistry in adult Anp32b −/− mice.
| Parameter | ||||
|---|---|---|---|---|
| Total protein (g/dl) | Total bilirubin (mg/dl) | Total cholesterol (mg/dl) | HDL cholesterol (mg/dl) | |
| +/+ average | 5.525 ± 0.09 | 0.2 ± 0.02 | 118.25 ± 3.3 | 60.63 ± 4.1 |
| –/– average | 5.212 ± 0.13 | 0.125 ± 0.02 | 100.38 ± 6.9 | 54.75 ± 3.0 |
| Average pairwise reduction | 5.54% ± 1.1% | 35.42% ± 8% | 14.03% ± 3.5% | 10.11% ± 3.5% |
| Statistical test | Signed-rank | Signed-rank | Signed-rank | Student’s t-test |
| P-value | < 0.001 | < 0.001 | < 0.001 | < 0.05 |
Indicated parameters demonstrated statistically significant changes between adult paired +/+ and −/− mice (n=8). Statistical tests were chosen based on Anderson-Darling normality.