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. 2015 Oct 21;65(1):63–75. doi: 10.1538/expanim.15-0039

Table 2. Mean (SD) biochemistry parameters following a single intraperitoneal injection of ketamine (80 mg/kg) and xylazine (10 mg/kg) administered to male Sprague Dawley rats (n=3/group) of different ages.

Biochemistry parameters (units) Normal values Age (months)

3 6 12 18
Glucose (mmol/l) 4.4–16.7 9.3 (1.3) 12.9 (3.2) 17.6 (6.0) 28.8 (9.0)
BUN (mmol/l) 3.9–8.2 9.6 (1.1) 9.9 (1.7) 11.8 (1.8) 13.0 (2.3)
Creatinine (mmol/l) 35–123 40.0 (3.5) 45.3 (5.8) 58.7 (8.3) 65.7 (16.0)
ALT (U/l) 28–40 55.7 (9.2) 48.7 (9.0) 56.0 (15.9) 62.0 (7.2)
ALP (U/l) 150–220 215.3 (53.4) 138.0 (28.2) 142.3 (23.7) 164.7 (35.3)
Total proteins (g/l) 58–66 64.6 (0.6) 61.1 (1.0) 56.1 (6.1) 59.4 (7.2)
Albumin (g/l) 33–46 32.8 (0.3) 31.5 (1.8) 28.3 (2.6) 28.3 (3.9)
Globulins (g/l) 17–30 31.8 (0.6) 29.6 (1.8) 27.8 (3.6) 31.1 (1.3)

ALP, alkaline phosphatase; ALT, alanine aminotransferase; BUN, blood urea nitrogen.