Table 1.
List of peptides used in this study. HLA restriction and full peptide sequence are listed in all but 3 cases. Sequences of the new HLA-A*0201-restricted Engrailed-2-derived epitopes, and the new HLA-DRB*0101-restricted epitopes from influenza haemagglutinin and 5T4 oncofetal protein will be published in other studies we are currently preparing.
| Origin | Protein | Amino acid residues | Peptide sequence | HLA restriction | Reference |
|---|---|---|---|---|---|
| Epstein–Barr virus | BMLF1 lytic protein | 280–288 | GLCTLVAML | A*0201 | Steven et al. (1997) |
| Influenza A | Matrix protein (MP) | 58–66 | GILGFVFTL | A*0201 | Bednarek et al. (1991) |
| Influenza A | Haemagglutinin (HA) | Putative | DRB*0101 | Babon et al. (2012) | |
| Zaire Ebola virus | Nucleoprotein | 150–158 | FLSFASLFL | A*0201 | Sundar et al. (2007) |
| Zaire Ebola virus | Nucleoprotein (NP) | 202–210 | RLMRTNFLI | A*0201 | Sundar et al. (2007) |
| Zaire Ebola virus | Nucleoprotein | 404–412 | KLTEAITAA | A*0201 | Sundar et al. (2007) |
| Type 1 diabetes | Glutamic acid decarboxylase (GAD65) | 114–123 | VMNILLQYVV | A*0201 | Panina-Bordignon et al. (1995) |
| Type 1 diabetes | Insulin β chain (InsB) | 10–18 | HLVEALYLV | A*0201 | Pinkse et al. (2005) |
| Type 1 diabetes | Islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) | 265–273 | VLFGLGFAI | A*0201 | Jarchum et al. (2008) |
| Type 1 diabetes | Preproinsulin (PPI) | 15–24 | ALWGPDPAAA | A*0201 | Skowera et al. (2008) |
| Tumour | Cadherin-3/P-Cadherin (CDH3) | 655–663 | FILPVLGAV | A*0201 | Imai et al. (2008) |
| Tumour | Engrailed-2 (EN2) | Putative | A*0201 | Morgan et al. (2011) | |
| Tumour | Glycoprotein 100 (gp100) | 280–288 | YLEPGPVTA | A*0201 | Kawakami et al. (1995) |
| Tumour | Insulin-like growth factor 2 mRNA binding protein 3 (IMP-3) | 199–207 | RLLVPTQFV | A*0201 | Tomita et al. (2011) |
| Tumour | Melanoma-associated antigen-1 (MAGE-A1) | 278–286 | KVLEYVIKV | A*0201 | Pascolo et al. (2001) |
| Tumour | Melanoma-associated antigen-3 (MAGE-A3) | 112–120 | KVAELVHFL | A*0201 | Chinnasamy et al. (2011) |
| Melanoma-associated antigen 3 (MAGE-A3) | 240–248 | YLEYRQVPG | A*0201 | Graff-Dubois et al. (2002) | |
| Tumour | NY-BR-1 | 904–912 | SLSKILDTV | A*0201 | Wang et al. (2006) |
| Tumour | Oncofetal protein, 5CT4 | Putative | DRB*0101 | Starzynska et al. (1994) | |
| Tumour | Prostatic acid phosphatase-3 (PAP-3) | 299–307 | ALDVYNGLL | A*0201 | Harada et al. (2003) |
| Tumour | Prostein | 31–39 | CLAAGITYV | A*0201 | Kiessling et al. (2004) |