Table 3. Univariate and multivariate analysis of factors associated with overall survival in patients receiving SIRT.

Variable	Univariate analysis				Multivariate analysis
	Hazard ratio	95% CI	P value		Hazard ratio	95% CI	P value
ECOG [0 & 1]	0.022	0.003-0.185	0.0005		0.039	0.004-0.352	0.0039
ECOG [2]	0.028	0.003-0.273	0.0021		0.064	0.0006-0.696	0.0239
Pre-treatment platelet	0.999	0.996-1.001	0.309
Post-treatment platelet	1	0.998-1.002	0.7323
Pre-neutrophil	1.059	0.961-1.166	0.2499
Post-neutrophil	1.151	1.071-1.238	0.0001
Pre-lymphocyte	0.831	0.596-1.159	0.2753
Post-lymphocyte	0.617	0.274-1.339	0.2437
Pre NLR	1.049	0.974-1.13	0.2075
Post NLR	1.014	1.005-1.024	0.0041		1.016	0.999-1.034	0.0662
ΔNLR	0.997	0.983-1.012	0.6836
Pre PLR	1.001	0.999-1.002	0.2624		1.003	1-1.005	0.0183
Post PLR	1.001	1-1.001	0.0422
ΔPLR	1.111	0.993-1.243	0.066		1.285	1.037-1.592	0.0219
Liver tumor volume	1.01	1.001-1.002	0.0005		1.001	1-1.002	0.0086
Liver tumor burden %	1.016	1.005-1.026	0.0042

SIRT, selective internal radiation therapy; ECOG, Eastern Cooperative Oncology Group; NLR, neutrophil-to-lymphocyte; PLR, platelet-to-lymphocyte ratios.