Table 2. Hemodynamic data.
Results are presented as medians and ranges.
| Control | Isoflurane | |||||
|---|---|---|---|---|---|---|
| T15 | T30 | Control T15 vs T30 (p-value) | T15 | T30 | Isoflurane T15 vs T30 (p-value) | |
| CI (l min−1 m−2) | 2.9 (2.3–3.6) | 2.7 (2.1–3.2) | 0.11 | 2.7 (1.6–5.7) | 2.6 (1.9–5.8) | 0.28 |
| HR (min−1) | 89 (53–106) | 90 (56–106) | 0.65 | 99 (76–112) | 88 (74–100) | 0.15 |
| MAP (mmHg) | 65 (47–80) | 66 (56–84) | 0.06 | 69 (59–85) | 57 (48–59) | 0.005 |
| MDAP (mmHg) | 57 (45–64) | 60 (43–71) | 0.06 | 62 (53–79) | 50 (45–57) | 0.005 |
| DDT (ms) | 447 (257–1215) | 489 (366–1070) | 0.60 | 721 (240–919) | 567 (339–937) | 0.33 |
| CVP (mmHg) | 9 (7–16) | 9 (7–16) | 1.0 | 10 (7–12) | 10 (7–13) | 0.82 |
| CSP (mmHg) | 14 (8–18) | 13 (7–18) | 0.39 | 10 (5–20) | 10 (6–19) | 0.44 |
| SVRI (dyn sec cm−5 m2) | 1555 (809–2454) | 1716 (1355–2193) | 0.31 | 1730 (850–2969) | 1364 (699–1965) | 0.04 |
| GEDI (ml m−2) | 642 (541–895) | 652 (594–883) | 0.78 | 642 (457–834) | 617 (479–802) | 0.92 |
| EVLWI (ml m−2) | 6.8 (5.7–10.0) | 6.3 (5.0–8.7) | 0.62 | 7.4 (4.0–10.7) | 7.0 (4.3–10.0) | 0.16 |
| LVEDP (mmHg) | 16 (8–33) | 15 (8–30) | 0.09 | 11 (8–37) | 13 (9–22) | 0.80 |
| SVV (%) | 11 (6–17) | 12 (5–18) | 0.64 | 12 (5–19) | 14 (8–16) | 0.43 |
| dp/dtmax (mmHg s−1) | 766 (507–1063) | 763 (500–887) | 0.65 | 748 (510–1350) | 651 (340–1143) | 0.02 |
| CFI (min−1) | 4.2 (3.5–5.0) | 3.7 (2.8–5.0) | 0.05 | 4.6 (2.5–8.1) | 3.9 (3.1–7.4) | 0.16 |
| COP (mmHg) | 39 (23–48) | 42 (28–44) | 0.25 | 35 (26–59) | 34 (27–42) | 0.11 |
| FLOW (ml/min) | 26 (10–38) | 22 (9–53) | 0.72 | 29 (7–68) | 23 (11–50) | 0.24 |
| Slope (B1) | 1.36 (0.48–2.71) | 1.29 (0.46–2.10) | 0.49 | 0.94 (0.50–4.82) | 2.03 (0.56–4.41) | 0.02 |
| CVR from Slope 1/B1 | 0.74 (0.37–2.10) | 0.78 (0.48–2.17) | 0.49 | 1.06 (0.21–2.02) | 0.51 (0.23–1.79) | 0.007 |
| CVR from CSP | 1.73 (1.21–3.92) | 1.83 (0.94–5.51) | 0.69 | 1.80 (0.78–8.83) | 1.35 (0.81–3.35) | 0.30 |
| CVR from LVEDP | 1.66 (0.81–4.05) | 1.86 (0.61–5.64) | 0.49 | 1.68 (0.79–5.38) | 1.77 (0.73–3.13) | 0.06 |
| CVR from COP | 0.74 (0.37–2.07) | 0.78 (0.46–2.13) | 0.44 | 1.06 (0.21–2.02) | 0.51 (0.23–1.79) | 0.006 |