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. 2016 Mar 9;6:22835. doi: 10.1038/srep22835

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Copyright © 2016, Macmillan Publishers Limited

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The classical Th2 cytokines such as IL-5, IL-13 and thymic stromal lymphopoietin (TSLP) were further measured by ELISA. The levels of serum IL-5, IL-13 and TSLP were significantly higher in patients with asthma (n = 44) compared with control subjects (n = 22) (A–C). Spearman’s rank correlation analysis showed a significant correlation between the serum IL-31 levels and the serum IL-5 levels (r = 0.34, p = 0.024), the serum IL-13 levels (r = 0.43, p = 0.003), the serum TSLP levels (r = 0.42, p = 0.004) (D–F). Data are presented as median with interquartile range. **p < 0.01, ***p < 0.001.