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. Author manuscript; available in PMC: 2016 Mar 9.

Published in final edited form as: Int J Obes (Lond). 2010 Aug 17;35(2):300–308. doi: 10.1038/ijo.2010.137

Table 4.

Relationships between genotypic variation and BMI and circulating CRP.

*FTO(rs9939609)*
	TT		AT		AA		Per allele effect	p
BMI	26.07 (25.98, 26.17)		26.37 (26.29, 26.45)		26.73 (26.59, 26.87)		0.32 (0.24, 0.40)	<0.0001
CRP	1.51 (1.48, 1.55)		1.55 (1.52, 1.58)		1.61 (1.56, 1.67)		1.03 (1.01, 1.05)	0.00

*CRP(rs3091244)*
	CC	CT	TT	CA	AT	AA	Per allele effect	p
BMI	26.32 (26.23, 26.41)	26.36 (26.27, 26.44)	26.24 (26.07, 26.42)	26.25 (26.02, 26.47)	26.29 (25.98, 26.61)	27.15 (26.02, 28.28)	−0.01 (−0.06, 0.04)	0.7
CRP	1.37 (1.34, 1.40)	1.61 (1.57, 1.64)	1.82 (1.74, 1.90)	1.71 (1.62, 1.81)	2.11 (1.95, 2.28)	2.56 (1.95, 3.37)	1.11 (1.10, 1.13)	<0.0001

Means (95%CI) by genotypes with linear regression derived, per allele effect estimates (assuming additivity).

CRP was log transformed for analyses hence geometric means are presented by genotype and a ratios of geometric for effect estimates.