Extended Data Figure 4. New subunit interfaces in apo-FluPol_C.

a, b, Two views of the interaction interface between PB2_NLS (green) and P3_endo (blue). Predicted polar contacts between the subunits are shown as dotted yellow lines. c, The interface between PB2_cap (green) and PB1_palm (orange). In all panels, residues at the interface were calculated using the ‘Protein interfaces, surfaces and assemblies’ service PISA at the European Bioinformatics Institute (http://www.ebi.ac.uk/pdbe/prot_int/pistart.html)⁴³.