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Induction of caspase-3 and caspase-9 activities after incubation with compounds 1–4 for 24 h. White, gray and black columns denote the control, or 5 and 10 µM sesquiterpene, respectively. * and ** denote p < 0.05 and p < 0.01, respectively, as compared with the control condition. The activities of caspase-3 and caspase-9 were determined with fluorimetric and colorimetric assay kits, respectively. Data are means ± SEM from three determinations.
