Table 2.
Sixty-one upregulated proteins under heat stress in the intestine of the sea cucumber A. japonicas.
| Accession Number | Protein Description | HS vs. Control | |
|---|---|---|---|
| Mean | SD | ||
| HSPs and Related Proteins | |||
| Unigene28963 | heat shock protein 90 | 6.10 | 4.25 |
| CL6821.Contig1 | heat shock protein 70 | 1.56 | 0.62 |
| CL5625.Contig2 | heat shock protein 110 | 1.41 | 0.22 |
| Unigene15437 | heat shock protein 10 | 1.20 | 0.01 |
| CL12434.Contig1 | heat repeat-containing protein 7A | 1.36 | 0.19 |
| Detoxification and Tissue Protection | |||
| Unigene61290 | glutathione S-transferase | 1.36 | 0.07 |
| CL6008.Contig2 | glutathione S-transferase α-4-like, partial | 2.23 | 0.72 |
| Unigene25399 | sigma class glutathione S-transferase 2 | 1.29 | 0.26 |
| CL7884.Contig2 | phospholipid hydroperoxide glutathione peroxidase | 1.45 | 0.16 |
| Unigene29285 | prostaglandin D2 synthase, hematopoietic-like | 1.53 | 0.35 |
| Unigene25766 | cytochrome P450 4V2-like | 2.43 | 1.45 |
| Cell Apoptosis and Proliferation | |||
| Unigene29013 | apoptosis-inducing factor 1, mitochondrial-like, partial | 1.28 | 0.20 |
| CL4411.Contig2 | prohibitin-like | 1.19 | 0.12 |
| CL2387.Contig1 | autocrine proliferation repressor protein A-like | 3.57 | 3.08 |
| Unigene33274 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 1.27 | 0.09 |
| CL10790.Contig2 | erlin-1 | 1.29 | 0.04 |
| Unigene35102 | mesoderm-specific transcript protein (MEST) | 2.61 | 2.19 |
| Lipid Transport and Metabolism | |||
| Unigene64084 | long-chain specific acyl-CoA dehydrogenase | 1.41 | 0.24 |
| Unigene20467 | long-chain specific acyl-CoA dehydrogenase, mitochondrial-like | 2.22 | 0.72 |
| Unigene22338 | short chain dehydrogenase/reductase family 16C, member 5-like | 1.74 | 0.58 |
| Unigene4389 | 17-β-hydroxysteroid dehydrogenase type 4 | 1.94 | 1.11 |
| Unigene5795 | 11-β-hydroxysteroid dehydrogenase | 2.54 | 1.24 |
| Unigene6420 | enoyl-CoA Hydratase family member-like | 1.62 | 0.33 |
| CL12084.Contig1 | enoyl-CoA hydratase, mitochondrial-like | 1.30 | 0.16 |
| CL759.Contig2 | hydroxyacyl-Coenzyme A dehydrogenase | 1.34 | 0.31 |
| Unigene19362 | epidermal retinol dehydrogenase 2-like | 1.97 | 0.83 |
| Unigene15259 | carnitine O-palmitoyltransferase 2, mitochondrial-like | 1.21 | 0.06 |
| Unigene11008 | non-specific lipid-transfer protein-like | 2.99 | 1.98 |
| CL4289.Contig1 | nuclear progesterone receptor | 1.46 | 0.23 |
| CL6901.Contig2 | 2′-deoxynucleoside 5′-phosphate N-hydrolase 1 | 1.43 | 0.27 |
| CL8136.Contig1 | acyl-CoA-binding protein like, ACBP2 | 2.33 | 1.46 |
| Unigene18754 | oxysterol-binding protein-related protein 9 | 1.20 | 0.18 |
| Carbohydrate Transport and Metabolism | |||
| Unigene2131 | lactase | 1.48 | 0.10 |
| Amino Acid Transport and Metabolism | |||
| CL4095.Contig2 | sphingosine-1-phosphate lyase 1 | 1.33 | 0.27 |
| Unigene23212 | branched-chain-amino-acid aminotransferase-like protein 1 | 1.39 | 0.32 |
| Energy Production and Conversion | |||
| CL10773.Contig1 | isocitrate dehydrogenase | 1.68 | 0.19 |
| Unigene18857 | electron transfer flavoprotein subunit α, mitochondrial-like | 1.27 | 0.25 |
| CL6007.Contig1 | aldehyde dehydrogenase, dimeric NADP-preferring isoform | 1.37 | 0.22 |
| Unigene22955 | α-methylacyl-CoA racemase-like | 1.65 | 0.66 |
| Unigene175 | d-glucosyl-N-acylsphingosine glucohydrolase | 1.85 | 0.31 |
| Unigene22578 | α-galactosidase | 1.91 | 1.26 |
| Unigene29260 | ATPase family AAA domain-containing protein 1 | 1.35 | 0.05 |
| CL5389.Contig1 | ATPase inhibitor, mitochondrial-like | 1.31 | 0.21 |
| Protein Synthesis | |||
| CL9215.Contig1 | aspartyl-tRNA synthetase | 1.17 | 0.11 |
| CL7807.Contig3 | RNA-binding motif protein, X chromosome | 1.25 | 0.19 |
| Unigene8195 | elongation factor Tu, mitochondrial-like | 1.34 | 0.20 |
| Others/Uncharacterized | |||
| Unigene49395 | toposome | 1.83 | 0.81 |
| Unigene28479 | natterin-3-like | 2.63 | 1.01 |
| CL6732.Contig2 | calpain-5 isoform 2 | 1.38 | 0.37 |
| Unigene22143 | phospholipase C delta isoform | 2.55 | 0.58 |
| CL1115.Contig1 | endophilin-B1-like isoform 1 | 1.32 | 0.19 |
| Unigene322 | myosin VIb-like | 1.32 | 0.24 |
| CL7807.Contig3 | atlastin-2 | 1.33 | 0.23 |
| CL9074.Contig2 | cysteine rich protein 1 | 1.59 | 0.18 |
| Unigene11767 | suppressor of G2 allele of SKP1 homolog | 1.53 | 0.14 |
| CL8638.Contig1 | development-specific protein LVN1.2 | 1.71 | 0.62 |
| Unigene22386 | uncharacterized | 1.39 | 0.35 |
| Unigene1947 | uncharacterized | 3.76 | 1.54 |
| Unigene5634 | uncharacterized | 1.66 | 0.38 |
| Unigene16247 | uncharacterized | 2.11 | 1.58 |
| Unigene62712 | uncharacterized | 11.32 | 9.13 |