Table 3.
Sixty-six downregulated proteins under heat stress in the intestine of the sea cucumber A. japonicas.
| Accession Number | Protein Description | HS vs. Control | |
|---|---|---|---|
| Mean | SD | ||
| Cytoskeletal Proteins | |||
| Unigene32477 | twitchin-like | 0.67 | 0.21 |
| Unigene32260 | laminin subunit α-like | 0.68 | 0.13 |
| CL221.Contig4 | α-actinin-like | 0.76 | 0.10 |
| Unigene3881 | galectin-9-like | 0.56 | 0.29 |
| Unigene27394 | fibrillin-1-like | 0.52 | 0.17 |
| CL5005.Contig4 | cohesin subunit SA-1-like | 0.69 | 0.25 |
| Unigene9716 | titin isoform 3 | 0.72 | 0.17 |
| CL3832.Contig7 | filamin-C isoform 1 | 0.83 | 0.01 |
| Unigene30625 | muscle M-line assembly protein unc-89-like | 0.71 | 0.10 |
| Transcription and Translation | |||
| Unigene29879 | 60S ribosomal protein L8-like | 0.79 | 0.11 |
| Unigene26472 | 60S ribosomal protein L6, partial | 0.82 | 0.15 |
| Unigene8941 | ribosomal protein L4, partial | 0.82 | 0.09 |
| CL1672.Contig2 | 60S ribosomal protein L10-like | 0.73 | 0.14 |
| CL4437.Contig3 | splicing factor, proline- and glutamine-rich | 0.62 | 0.05 |
| CL5572.Contig1 | THO complex subunit 4 | 0.64 | 0.25 |
| Unigene22920 | small nuclear ribonucleoprotein-associated proteins B and B′ | 0.81 | 0.12 |
| Unigene15894 | malectin | 0.75 | 0.08 |
| DNA Replication and Repair | |||
| CL1035.Contig9 | histone H3.3 | 0.66 | 0.29 |
| Unigene5846 | histone H1-β, late embryonic | 0.61 | 0.05 |
| CL5357.Contig1 | legumain-like | 0.67 | 0.20 |
| CL64.Contig2 | poly(ADP-ribose) polymerase pme-5-like | 0.77 | 0.08 |
| Unigene9968 | ATP-binding cassette, sub-family C, member 9-like | 0.69 | 0.01 |
| Amino Acid Transport and Mechanism | |||
| CL4631.Contig1 | choline dehydrogenase, mitochondrial-like | 0.65 | 0.17 |
| Unigene11760 | branched-chain-amino-acid aminotransferase, cytosolic | 0.71 | 0.08 |
| CL3226.Contig1 | tyrosine aminotransferase-like | 0.66 | 0.28 |
| Unigene25781 | aminopeptidase N-like | 0.72 | 0.13 |
| CL12737.Contig1 | glutamyl aminopeptidase | 0.79 | 0.16 |
| CL2682.Contig1 | cytosolic serine hydroxymethyltransferase | 0.73 | 0.08 |
| CL9582.Contig2 | xaa-Pro aminopeptidase 1 isoform X3 | 0.76 | 0.09 |
| Unigene36365 | betaine homocysteine S-methyltransferase 1 | 0.58 | 0.22 |
| Unigene3911 | betaine homocysteine S-methyltransferase 1-like | 0.38 | 0.10 |
| Lipid Transport and Mechanism | |||
| Unigene27722 | peroxisomal bifunctional enzyme-like | 0.78 | 0.14 |
| Unigene10407 | peroxisomal bifunctional enzyme | 0.81 | 0.07 |
| CL8765.Contig2 | dihydropteridine reductase | 0.74 | 0.09 |
| CL1598.Contig1 | γ-butyrobetaine dioxygenase-like | 0.60 | 0.22 |
| Carbohydrate Transport and Metabolism | |||
| Unigene27857 | α-mannosidase 2C1-like | 0.47 | 0.24 |
| Unigene18547 | pyruvate carboxylase, mitochondrial | 0.73 | 0.15 |
| Hormonal and Nerve Regulation | |||
| Unigene25501 | thyroid hormone-induced protein B-like | 0.41 | 0.28 |
| CL9528.Contig2 | proactivator polypeptide | 0.72 | 0.23 |
| Unigene19435 | angiotensin-converting enzyme | 0.38 | 0.18 |
| CL7652.Contig1 | potassium channel tetramerization domain containing 6-like | 0.37 | 0.29 |
| CL5238.Contig2 | glutamate receptor 1-like | 0.68 | 0.08 |
| Others/Uncharacterized | |||
| Unigene1888b1 | sterigmatocystin biosynthesis dehydrogenase stcV | 0.65 | 0.26 |
| CL5732.Contig1 | N-acetylated-α-linked acidic dipeptidase 2-like isoform 1 | 0.58 | 0.11 |
| CL9717.Contig2 | peroxiredoxin-4-like | 0.53 | 0.07 |
| Unigene25753 | homogentisate 1,2-dioxygenase | 0.56 | 0.32 |
| CL2303.Contig2 | cathepsin L | 0.70 | 0.26 |
| Unigene8231 | α-parvin-like | 0.77 | 0.11 |
| CL7154.Contig1 | sorcin | 0.82 | 0.10 |
| Unigene32921 | thiopurine S-methyltransferase isoform X2 | 0.75 | 0.07 |
| CL2660.Contig13 | phosphatidylinositol-binding clathrin assembly protein unc-11-like isoform 6 | 0.80 | 0.09 |
| Unigene15838 | cytochrome P450 2N2 | 0.70 | 0.10 |
| CL2540.Contig2 | cytochrome P450 2U1-like | 0.58 | 0.05 |
| Unigene23131 | oocyst wall protein 4 precursor | 0.58 | 0.10 |
| CL4607.Contig1 | uterine-ovary specific-44 protein | 0.79 | 0.14 |
| CL10965.Contig2 | MAM and LDL-receptor class A domain-containing protein 2-like | 0.73 | 0.13 |
| Unigene11852 | uncharacterized | 0.74 | 0.17 |
| Unigene8201 | uncharacterized | 0.62 | 0.21 |
| Unigene63234 | uncharacterized | 0.55 | 0.34 |
| Unigene11761 | uncharacterized | 0.77 | 0.08 |
| CL11132.Contig3 | uncharacterized | 0.59 | 0.23 |
| Unigene23211 | uncharacterized | 0.77 | 0.20 |
| CL12015.Contig1 | uncharacterized | 0.58 | 0.19 |
| CL709.Contig5 | uncharacterized | 0.37 | 0.27 |
| Unigene8605 | uncharacterized | 0.78 | 0.03 |
| CL3869.Contig4 | uncharacterized | 0.58 | 0.12 |