Table 4.
Pathway ID | Pathway Term | All Proteins with Pathway Annotation (2664) | Differential Proteins with Pathway Annotation (100) | p-Value |
---|---|---|---|---|
Upregulated Pathways | ||||
ko00480 | Glutathione metabolism | 30 (1.13%) | 6 (6%) | 1.37 × 10−3 |
ko00980 | Metabolism of xenobiotics by cytochrome P450 | 46 (1.73%) | 7 (7%) | 1.51 × 10−3 |
ko00071 | Fatty acid metabolism | 60 (2.25%) | 8 (8%) | 2.31 × 10−3 |
ko03320 | Peroxisome proliferator-activated receptors (PPAR) signaling pathway | 64 (2.4%) | 8 (8%) | 4.35 × 10−3 |
ko00120 | Primary bile acid biosynthesis | 56 (2.1%) | 7 (7%) | 8.82 × 10−3 |
ko00982 | Drug metabolism-cytochrome P450 | 51 (1.91%) | 6 (6%) | 1.10 × 10−2 |
ko05215 | Prostate cancer | 37 (1.39%) | 5 (5%) | 1.13 × 10−2 |
Downregulated Pathways | ||||
ko05322 | Systemic lupus erythematosus | 23 (0.86%) | 4 (4%) | 9.55 × 10−3 |
ko04614 | Renin-angiotensin system | 51 (1.91%) | 6 (6%) | 1.10 × 10−2 |