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PROK1-V67I and WT did not alter cell proliferation and tubal formation. HEK 293 and HTR-8/SV neo cells were transiently transfected with control vector, WT, or variant PROK1 construct. (A) Cell numbers in proliferation of HEK293 and HTR-8/SV neo cells were measured, and no significant differences were detected between each group; (B) Photographs and quantification of tube formation in each group of HTR-8/SV neo and HEK293 cells, and no significant difference (N.S.) was detected.
