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. 2016 Jan 27;17(2):164. doi: 10.3390/ijms17020164

Figure 1.

Figure 1

Possible participation of catecholic metabolites known to be present in various regions of the brain that may be incorporated into neuromelanin [7,8]. In addition to dopamine (DA) and norepinephrine (NE) and the corresponding Cys-derivatives, these other metabolites are also thought to be incorporated into neuromelanin [9,10]. substantia nigra, SN; locus coeruleus, LC; 3,4-dihydroxyphenylethanol, DOPE; 3,4-dihydroxyphenylethylene glycol, DOPEG; 3,4-dihydroxyphenylacetic acid, DOPAC; 3,4-dihydroxyphenylmandelic acid, DOMA; 3,4-dihydroxyphenylalanine, DOPA; cysteine, cys. The (O) represents the oxidants. Adapted from [10] with minor modifications.