Figure 5.

Modulation of connexin 43 expression affects proliferation and viability of FMC2u cells. (A) Graphical representation of fold protein induction from western blot analysis of Cx43 in FMC2u cells transfected with GFP-Cx43 cDNA vectors; (B) Graphical representation of fold protein induction from western blot analysis of Cx43 in FMC2u cells transfected with siRNA of Cx43; (C) Viability and (D) Total cell count either overexpressing (OE) Cx43 or with silenced (siRNA) Cx43 compared to normal unmodified cells; (E) Graphical representation of cleaved caspase-3 expression in FMC2u cells post transfection. All experiments conducted with a sample size of n = 3. * p-value < 0.05 compared to respective transfection control.