Table 1.
Clinical Variable | Controls (n = 74) Median (Range) | Before Antibiotic Treatment (n = 137) Median (Range) | After Antibiotic Treatment (n = 137) Median (Range) | p Value UT/C b | p Value UT/T c |
---|---|---|---|---|---|
Age | 59.89 ± 11.04 d | 64.89 ± 20.89 d | - | p = 0.057 | - |
Gender | - | - | - | - | |
Male | 49 (66.2%) | 87 (63.5%) | - | p = 0.694 | - |
Female | 25 (33.8%) | 50 (36.5%) | - | - | - |
CRP (mg/dL) | 0.40 (0.2–1.50) | 10.1 (0.50–33.30) | 2.10 (0.10–17.20) | p < 0.001 | p < 0.001 |
WBCs (cells/mm3) | 5900 (2980–13,700) | 12,030 (3560–32,480) | 8280 (3300–28,180) | p < 0.001 | p < 0.001 |
Neutrophils (cells/mm3) | 3580 (1078–9946) | 8715 (1032–29,686) | 5616 (1518–25,841) | p < 0.001 | p < 0.001 |
PSI score | - | 83.89 ± 36.63 d | - | - | - |
CURB-65 score | - | 1.12 ± 0.94 d | - | - | - |
APACHE II score | - | 10.20 ± 5.27 d | - | - | - |
Hospital length of stay (Days) | - | 10.37 ±14.54 d | - | - | - |
CRP, C-reactive protein; WBCs, white blood cells; C, controls; UT, patients with CAP before they received antibiotic treatment; T, patients with CAP after they received antibiotic treatment; a p < 0.05 was considered significant; b The statistical difference was analyzed by the Mann–Whitney U-test; c The statistical difference was analyzed by the Wilcoxon signed-ranks test; d Mean ± S.D.