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Atrogin-1 deficiency leads to an autophagy-related ultrastructural muscle pathology. (A–D) Electron micrographs of cardiomyocytes (heart) and skeletal muscle cells (skm) of Atrogin-1 morphants and embryos injected with control Morpholino at 72 hpf. Asterisks indicate vesicular bodies, arrowhead indicates dysmorphic mitochondria, scale bar = 2 µm.
