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. 2016 Feb 2;17(2):204. doi: 10.3390/ijms17020204

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Structure of the intergenic region (IGR) internal ribosome entry site (IRES). The structure of the IGR-IRES in MrTV genome was predicted using the Mfold web server (http://mfold.rna.albany.edu//?q=mfold/RNA-Folding-Form). MrTV had a bulge sequence (UGGAUACCCAU and UAAGGCUU) in the IGR IRES. Additional stem loop structures and nucleotide sequences in the bulge regions were present in MrTV (indicated in bold). The red stars and dots indicate nucleotide interactions in pseudoknots and stems. The different color styles correspond to the different stems. CrPV (cricket paralysis virus; type species of Cripavirus), ABPV (Acute bee paralysis virus; type species of Aparavirus).