Fig. 1.
RA acts synergistically with IL-2 to induce cytokine production in human ILCs. Concentrations of IL-5 (A), IL-13 (B), and IFN-γ (C) were measured in culture supernatants of ILC1, ILC2, and ILC3 cells incubated with the indicated stimuli. Cytokine data were normalized to 2,000 ILCs per 200 μl culture volume. Combined data of nine independent experiments and subjects are shown. * p<0.05, ** p<0.01 (cultures with IL-2 + RA vs. cultures with IL-2 or RA alone).