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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: Arch Biochem Biophys. 2016 Jan 16;592:60–75. doi: 10.1016/j.abb.2016.01.010

Figure 4.

Figure 4

Heme biosynthesis pathway. ALA: 5-aminolevulinic acid, ALAS: ALA synthase, PBGS: porphobilinogen synthase, ALAD: ALA dehydratase, PBGD: porphobilinogen deaminase, UROS: uroporphyrinogen synthase, UROD: uroporphyrinogen decarboxylase, PBR: peripheral-type benzodiazepine receptor, CPO: coproporphyrinogen III oxidase, PPO: protoporphyrinogen IX oxidase, FC: Ferrochelatase, IMM: inner mitochondrial membrane, IMS: intermembrane space, OMM: outer mitochondrial membrane.