Table 2.

Sample size estimation based on four scenarios with small to medium effect sizes

Scenario	Effect size (d)	ICC	Standard care	Intervention	Time points	Alpha	Tails	Power
Scenario 1	0.25	0.3	115	115	4	0.05	2	0.80
Scenario 2	0.3	0.3	80	80	4	0.05	2	0.80
Scenario 3	0.35	0.3	59	59	4	0.05	2	0.80
Scenario 4	0.4	0.3	46	46	4	0.05	2	0.81