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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Am J Gastroenterol. 2015 Sep 8;110(10):1450–1459. doi: 10.1038/ajg.2015.283

Figure 3. Chronic liver injury due to metaclopramide.

Figure 3

A. In the initial biopsy, taken 89 days after DILI onset, there is a mild portal infiltrate with periductal inflammation and duct injury (arrowhead). No fibrosis was present.(Magnification 400 ×) B. Visible bile (arrows) was present in the parenchyma. (Magnification 600 ×) C. Enzyme abnormalities persisted and a second biopsy, taken 492 days after DILI onset, showed chronic cholestatic changes with marked ductular reaction and ductopenia. The portal areas were greatly expanded by fibrosis. (Magnification 200 ×).

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