Table 2.

Selected examples of investigations where the anti-tumor agent was protected by an NP during transport through the body and where the antineoplastic effect was expressed prolonged survival

Nanoparticle	Targeting ligand	Therapeutic agent	Tumor	Animal	Ref.
Polymer	Biotin	Paclitaxel + tariquidar	“transformed murine”	Mice	[153]
Polymer	None	Dox/curcumin	Four human malignancies	Mice	[265]
Liposome	Peptide	Dox	Human neuroblastoma	Mice	[266]
Chitosan-NP	mirRNA	Paclitaxel	Human ovarian cancer	Mice	[267]
Polymer	Local injector	Dithiazanin	MGB	Rats	[268]
Polymer	Abs, vs ABC G2	Paclitaxel + siRNA	Human breast cancer	Mice
Polymer	None stated	Dox + Mitomyzin	Human breast cancer	Mice	[269]
Polymer	Photodynamic and chemotherapy	Dox	Human breast cancer	Mice	[270]

GR growth reduction, PS prolonged survival, Wt wild type