Figure 3. HS(3–4)c Trp is inactive.
A. Arthritis day of onset in DBA/1 CIA mice treated with HS(3–4)c Trp (administered ip weekly at a dose of 360 pg/gr- blue) or with PBS (black). N=10 per group. B. Arthritis incidence curves of CIA mice treated with 360 pg/gr of HS(3–4)c Trp (blue) or PBS (black). N=10 per group. C. Arthritis scores of CIA mice treated with 360 pg/gr of HS(3–4)c Trp (blue) or with PBS (black). N=10 per group; D. Comparative micro-CT images of paws of CIA mice treated with PBS (upper panel) or HS(3–4)c Trp, 360 pg/gr (lower panel); E. OCs were counted in the joints of CIA mice treated with 360 pg/gr HS(3–4)c Trp (blue) or PBS (black) as above. N=5 per group.