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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Arthritis Rheumatol. 2015 May;67(8):2061–2070. doi: 10.1002/art.39158

Table I.

Differential inhibition of SE-activated NO signaling by cDKCLA compounds

cDKCLA compound
IC50 (M)
HS(4–4)c Trp 1.6 × 10−12
HS(3–3)c Trp 1.8 × 10−12
HS(6–4)c Trp 6.3 × 10−9
HS(4–6)c Trp 5.6 × 10−7
HS(6–2)c Trp 7.7 × 10−7
HS(3–4)c Trp 4.3 × 10−6